Pochettino, who steered the Saints to an eighth-place finish in the 2013/14 campaign, will bring his backroom staff with him to White Hart Lane, with assistant head coach Jesus Perez, first-team coach Miguel D’Agostino and goalkeeper coach Toni Jimenez following him in making the switch to the London club.
Commenting on the appointment, Spurs chairman Daniel Levy told the club’s official website: “In Mauricio I believe we have a Head Coach who, with his high energy, attacking football, will embrace the style of play we associate with our Club.
“He has a proven ability to develop each player as an individual, whilst building great team spirit and a winning mentality.
“We have a talented squad that Mauricio is excited to be coaching next season.”
Pochettino, meanwhile, has expressed his delight at being handed the reins at Spurs, saying: “This is a Club with tremendous history and prestige and I am honoured to have been given this opportunity to be its Head Coach.
“There is an abundance of top-class talent at the Club and I am looking forward to starting work with the squad.
“Tottenham Hotspur has a huge following across the world and I have great admiration for the passion the fans show for this team.