Connect with us

Hi, what are you looking for?

top
Capital News
The US, the European Union and others have granted temporary approval for the use of remdesivir

Capital Health

WHO advises against remdesivir for coronavirus treatment

The US, the European Union and others have granted temporary approval for the use of remdesivir © POOL/AFP/File / Ulrich Perrey

Paris, France, Nov 20 – The anti-viral drug remdesivir should not be used to treat Covid-19 patients no matter how severe their illness as it has “no important effect” on survival chances, the World Health Organization said Friday.

Denting hopes in one of the few treatments that had shown some initial promise in severe patients, a WHO Guideline Development Group (GDG) of international experts said there was “no evidence based on currently available data that it does improve patient-important outcomes”.

The United States, the European Union and other countries have granted temporary approval for the use of remdesivir after initial research showed it may shorten recovery time in some coronavirus patients.

President Donald Trump was treated with remdesivir among other medicines after he tested positive for Covid-19 in October.

Friday’s WHO recommendation was based on four international randomised trials among more than 7,000 patients hospitalised with the virus.

Publishing updated treatment guidance in the BMJ medical journal, the panel acknowledged that their recommendation does not mean that remdesivir has no benefit for patients.

But based on the latest figures, costs and delivery methods, it advised “against administering remdesivir in addition to usual care for the treatment of patients hospitalised with Covid-19, regardless of disease severity”.

The panel recommended that remdesivir trials continued, however, adding that their advice didn’t constitute proof that the treatment couldn’t work in Covid-19 cases.

“That’s why it’s a conditional recommendation. (There may) still be potential small benefit, maybe in a subgroup (of patients),” Janet Diaz, the WHO’s head of clinical care, told reporters on Friday.

Advertisement. Scroll to continue reading.

“Is there a subgroup that may benefit more, such a severe patients versus critical patients”?

Manufacturer Gilead said that remdesivir was recognised as Covid-19 treatment by several official health agencies, including the US National Institutes of Health and Infectious Diseases of America, based on “robust data from several randomised control trials”.

“We regret that the WHO recommendation do not take this data into account even as the number of new cases globally is increasing considerably,” it said.

– ‘Expensive drug’ –

The US pharma giant said last month that the drug had boosted 2020 third quarter sales by almost $900 million.

Initially developed as a treatment for the Ebola virus, remdesivir was found in one study published in May to reduce the length of hospital stays for Covid-19 sufferers from 15 to 11 days on average.

A subsequent WHO pre-print however found the drug “appeared to have little or no effect” on mortality or length of hospitalisation among more than 11,000 hospitalised patients across 30 countries.

Peter Horby, professor of Emerging Infectious Diseases and Global Health at Oxford’s Nuffield Department of Medicine, said the WHO’s recommendation would require a rethink in how hospitalised Covid-19 cases are treated.

“Remdesivir is an expensive drug that must be given intravenously for five to ten days, so this recommendation will save money and other healthcare resources,” he said.

Advertisement. Scroll to continue reading.

Comments
Advertisement

More on Capital News

NATIONAL NEWS

NAIROBI, Kenya, Jan 29 — The Ministry of Foreign Affairs has termed recently published notices on an imminent threat in Kenya by various embassies...

Kenya

  NAIROBI, Kenya, Jan 28 – Police have arrested a man in Kaminon village, Nandi County who slashed his brother to death over a...

Kenya

NAIROBI, Kenya, Jan 27 – Wiper leader Kalonzo Musyoka has revealed that the One Kenya Alliance (OKA) had agreed to have him as presidential...

County News

NAIROBI, Kenya, Jan 28 — The body of a seven-year-old boy who went missing on Sunday has been recovered in Nairobi’s Dagoretti area after...

TERROR ALERT

NAIROBI, Kenya, Jan 28 — The United States Embassy in Nairobi has issued a security alert warning of a possible terrorist attack in Kenya....

AUGUST 9 COUNTDOWN

NAIROBI, Kenya, Jan 28 – Deputy President William Ruto and Amani National Congress leader Musalia Mudavadi staged a show of political bromance in Western...

Kenya

NAIROBI, Kenya, Jan 28 – President Uhuru Kenyatta on Friday met with top security officials amid a looming terror threat in the country. Warnings...

AUGUST 9 COUNTDOWN

NAIROBI, Kenya, Jan 28 — Wiper Party leader Kalonzo Musyoka who prides himself as the kingpin of the Ukambani region begun his tour of...