Scottish First Minister Nicola Sturgeon said a second independence vote was now “highly likely” after a 2014 referendum backed staying in the UK, and the Scottish parliament was due to meet for an emergency session early Saturday.
In Northern Ireland, the nationalist Sinn Fein party seized on the result to call for a vote on reunification with the Irish Republic.
The British vote will stoke fears of a domino-effect of exit votes in eurosceptic member states that could imperil the integrity of the bloc.
Dutch far-right MP Geert Wilders and French National Front leader Marine Le Pen immediately called for referendums on EU membership in their own countries.
Germany took a more measured approach, its foreign office tweeting that “we are off now to an Irish pub to get decently drunk. And from tomorrow on we will again work for a better Europe!”
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