Biden placed the call after thousands of people demonstrating against a film mocking Islam made in the United States attacked the embassies of the United States, Britain and Germany in the Sudanese capital.
A White House statement said Biden expressed “his concern for the security of the United States Embassy and other foreign missions in Khartoum.”
“Vice President Biden reaffirmed the responsibility of the Government of Sudan to protect diplomatic facilities and stressed the need for the Government of Sudan to ensure the protection of diplomats in Khartoum.
“Vice President Biden emphasized that the highest priority of the United States is the safety of the US diplomatic presence abroad.”
Guards on the roof of the American embassy in Khartoum fired warning shots as a security perimeter was breached and dozens of Islamic flag-waving protesters scaled an outer wall, an AFP reporter in Khartoum said Friday.
President Barack Obama has also made several calls to foreign leaders in nations where raging violence has targeted US embassies and consulates, including those of Egypt, Libya and Yemen.
Obama earlier Friday traveled to Andrews Air Force Base outside Washington to witness the return home of the remains of four Americans killed when a mob attacked the US consulate in Benghazi, including US ambassador to Libya Chris Stevens.